Promethazine codeine syrup - An Overview
Promethazine codeine syrup - An Overview
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Promethazine hydrochloride happens as being a white to faint yellow, practically odorless, crystalline powder which gradually oxidizes and turns blue on extended publicity to air.
Just take this medication exactly as prescribed to lower the chance of addiction. Ask your physician or pharmacist For additional details.
For instance, quite a few reported cases of Loss of life happened while in the article-operative interval pursuing tonsillectomy and/or adenoidectomy, and plenty of of the kids experienced proof of becoming extremely-rapid metabolizers of codeine. On top of that, young children with obstructive sleep apnea who're handled with codeine for article-tonsillectomy and/or adenoidectomy agony may be particularly delicate to its respiratory depressant impact. As a result of possibility of existence-threatening respiratory despair and Dying:
Absorption Codeine is absorbed within the gastrointestinal tract with most plasma concentration developing 60 minutes post administration. The presence of the substantial-fat, large-calorie meal didn't significantly impression the PK of codeine.
This medication might interfere with certain lab checks (including urine pregnancy tests, skin allergy assessments), quite possibly producing Bogus exam success. Ensure that lab personnel and your Medical practitioners know you use this drug.
Promethazine really should be applied cautiously in persons with heart problems or with impairment of liver purpose.
Thing to consider should be specified on the discontinuation of promethazine HCl and to the usage of other medications if these reactions occur. Respiratory depression, nightmares, delirium, and agitated conduct have also been reported in some of these individuals.
This is not a whole listing of doable Unwanted side effects. Should you see other Unwanted effects not outlined earlier mentioned, Get hold of your medical doctor or pharmacist.
Instruct nursing moms to talk to the infant's medical professional promptly if they notice these signs and, if they can't get to the medical doctor right away, to take the baby to an emergency room or call 911 (or neighborhood crisis services).
The vast majority of scientific studies inspecting the usage of promethazine in pregnancy didn't discover an association with a heightened danger of congenital anomalies. While in the several studies reporting an Affiliation, no constant sample of malformations was famous.
Opioid analgesics and antitussives, such as codeine, one of several Lively elements in Promethazine HCl and Codeine Phosphate Oral Alternative, shouldn't be used in sufferers with acute febrile illness connected to successful cough or in individuals with Serious respiratory disease exactly where interference with ability to very clear the tracheobronchial tree of secretions would have a deleterious effect on the affected individual’s respiratory functionality.
The opioid antagonists, naloxone and nalmefene, are certain antidotes Promethazine codeine syrup for respiratory melancholy resulting from opioid overdose. For clinically substantial respiratory or circulatory depression secondary to codeine overdose, administer an opioid antagonist. An antagonist shouldn't be administered inside the absence of clinically major respiratory despair. Since the period of opioid reversal is predicted to get lower than the duration of action of codeine in Promethazine HCl and Codeine Phosphate Oral Option, meticulously keep an eye on the individual until eventually spontaneous respiration is reliably reestablished.